An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing

An improved Tet-on system in microRNA overexpression and CRISPR/Cas9-mediated gene editing

Abstract Background Tetracycline (Tet)-regulated expression system has become a widely applied tool to control gene activity. This study aimed to improve the Tet-on system with superior regulatory characteristics. Results By comprehensively comparing factors of transactivators, Tet-responsive elemen...

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Bibliographic Details
Main Authors: Kang Kang, Lian Huang, Qing Li, Xiaoyun Liao, Quanjin Dang, Yi Yang, Jun Luo, Yan Zeng, Li Li, Deming Gou
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Animal Science and Biotechnology
Subjects:
CRISPR/Cas9
Doxycycline
microRNA
NFAT5
Tetracycline
Online Access:http://link.springer.com/article/10.1186/s40104-019-0354-5

Internet

http://link.springer.com/article/10.1186/s40104-019-0354-5

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