Mitotic spindle scaling during Xenopus development by kif2a and importin α

Early development of many animals is characterized by rapid cleavages that dramatically decrease cell size, but how the mitotic spindle adapts to changing cell dimensions is not understood. To identify mechanisms that scale the spindle during Xenopus laevis embryogenesis, we established an in vitro...

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Bibliographic Details
Main Authors: Jeremy D Wilbur, Rebecca Heald
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/00290