Inflammatory Conditions Dictate the Effect of Mesenchymal Stem or Stromal Cells on B Cell Function

Inflammatory Conditions Dictate the Effect of Mesenchymal Stem or Stromal Cells on B Cell Function

The immunomodulatory capacity of mesenchymal stem or stromal cells (MSC) makes them a promising tool for treatment of immune disease and organ transplantation. The effects of MSC on B cells are characterized by an abrogation of plasmablast formation and induction of regulatory B cells (Bregs). It is...

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Bibliographic Details
Main Authors: Franka Luk, Laura Carreras-Planella, Sander S. Korevaar, Samantha F. H. de Witte, Francesc E. Borràs, Michiel G. H. Betjes, Carla C. Baan, Martin J. Hoogduijn, Marcella Franquesa
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Immunology
Subjects:
B cell
immunomodulation
mesenchymal stem cell
plasmablast
regulatory B cell
indoleamine 2,3-dioxygenase
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01042/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01042/full

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