Platycodin D inhibits platelet function and thrombus formation through inducing internalization of platelet glycoprotein receptors

Platycodin D inhibits platelet function and thrombus formation through inducing internalization of platelet glycoprotein receptors

Abstract Background Platycodin D (PD) is one of the major bioactive components of the roots of Platycodon grandiflorum and possesses multiple biological and pharmacological properties, such as antiviral, anti-inflammatory, and anti-cancer activities. However, whether it affects platelet function rem...

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Bibliographic Details
Main Authors: Qi Luo, Guangyu Wei, Xiaoqing Wu, Kai Tang, Mengdi Xu, Yulu Wu, Yun Liu, Xiaoqian Li, Zengtian Sun, Wen Ju, Kunming Qi, Chong Chen, Zhiling Yan, Hai Cheng, Feng Zhu, Zhenyu Li, Lingyu Zeng, Kailin Xu, Jianlin Qiao
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Journal of Translational Medicine
Subjects:
Platycodin D
Platelet
Glycoprotein receptors
Internalization
Hemostasis
Arterial thrombosis
Online Access:http://link.springer.com/article/10.1186/s12967-018-1688-z

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http://link.springer.com/article/10.1186/s12967-018-1688-z

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