In Vitro and In Vivo Antimalarial Activity of LZ1, a Peptide Derived from Snake Cathelicidin

In Vitro and In Vivo Antimalarial Activity of LZ1, a Peptide Derived from Snake Cathelicidin

Antimalarial drug resistance is an enormous global threat. Recently, antimicrobial peptides (AMPs) are emerging as a new source of antimalarials. In this study, an AMP LZ1 derived from snake cathelicidin was identified with antimalarial activity. In the in vitro antiplasmodial assay, LZ1 showed stro...

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Bibliographic Details
Main Authors: Yaqun Fang, Xiaoqin He, Pengcheng Zhang, Chuanbin Shen, James Mwangi, Cheng Xu, Guoxiang Mo, Ren Lai, Zhiye Zhang
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Toxins
Subjects:
antimicrobial peptide
malaria
cytokine
pyruvate kinase
ATP
Online Access:https://www.mdpi.com/2072-6651/11/7/379

Internet

https://www.mdpi.com/2072-6651/11/7/379

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