Comparison of the NMR and the Acid Value Determination Methods for Quality Control of Input Polysorbates

Polysorbates (PS) are the most common non-ionic surfactants used in protein formulations. Their degradation has been studied intensively in recent years. Ester bond hydrolysis is one of many pathways of PS degradation that can lead to accumulation of free fatty acids (FFAs) and particle formation. T...

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Bibliographic Details
Main Authors: Ema Valentina Brovč, Stane Pajk, Roman Šink, Janez Mravljak
Format: Article
Language:English
Published: Slovenian Chemical Society 2019-12-01
Series:Acta Chimica Slovenica
Subjects:
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/5144