Partial Surface Modification of Low Generation Polyamidoamine Dendrimers: Gaining Insight into their Potential for Improved Carboplatin Delivery

Partial Surface Modification of Low Generation Polyamidoamine Dendrimers: Gaining Insight into their Potential for Improved Carboplatin Delivery

Carboplatin (CAR) is a second generation platinum-based compound emerging as one of the most widely used anticancer drugs to treat a variety of tumors. In an attempt to address its dose-limiting toxicity and fast renal clearance, several delivery systems (DDSs) have been developed for CAR. However,...

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Bibliographic Details
Main Authors: Dai Hai Nguyen, Long Giang Bach, Diem-Huong Nguyen Tran, Van Du Cao, Thi Nhu Quynh Nguyen, Thi Thu Hong Le, Thach Thao Tran, Thai Thanh Hoang Thi
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Biomolecules
Subjects:
carboplatin
cancer treatment
low generation polyamidoamine (PAMAM) dendrimer
surface modification
drug delivery systems
Online Access:https://www.mdpi.com/2218-273X/9/6/214

Internet

https://www.mdpi.com/2218-273X/9/6/214

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