Structural insights into the inhibition of bacterial RecA by naphthalene polysulfonated compounds

Summary: As a promising target for alternative antimicrobials, bacterial recombinase A (RecA) protein has attracted much attention for its roles in antibiotic-driven SOS response and mutagenesis. Naphthalene polysulfonated compounds (NPS) such as suramin have previously been explored as antibiotic a...

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Bibliographic Details
Main Authors: Ziyuan Zhou, Qing Pan, Xinchen Lv, Jing Yuan, Yang Zhang, Ming-Xia Zhang, Ming Ke, Xiao-Mei Mo, Yong-Li Xie, Yingxia Liu, Ting Chen, Mingchan Liang, Feng Yin, Lei Liu, Yiqing Zhou, Kun Qiao, Rui Liu, Zigang Li, Nai-Kei Wong
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220311494