Cyclosporin a inhibits rotavirus replication and restores interferon-beta signaling pathway in vitro and in vivo.

Rotavirus (RV) is the most common cause of severe diarrhea among infants and young children. Currently, there is no specific drug available against rotavirus, largely due to the lack of an ideal target molecule which has hampered drug development. Our previous studies have revealed that cyclosporin...

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Bibliographic Details
Main Authors: Zigang Shen, Haiyang He, Yuzhang Wu, Jintao Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3749198?pdf=render