Resolving the heterogeneity of diaphragmatic mesenchyme: a novel mouse model of congenital diaphragmatic hernia

Resolving the heterogeneity of diaphragmatic mesenchyme: a novel mouse model of congenital diaphragmatic hernia

Congenital diaphragmatic hernia (CDH) is a relatively common developmental defect with considerable mortality and morbidity. Formation of the diaphragm is a complex process that involves several cell types, each with different developmental origins. Owing to this complexity, the aetiology of CDH is...

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Bibliographic Details
Main Authors: Louise Cleal, Sophie L. McHaffie, Martin Lee, Nick Hastie, Ofelia M. Martínez-Estrada, You-Ying Chau
Format: Article
Language:English
Published: The Company of Biologists 2021-01-01
Series:Disease Models & Mechanisms
Subjects:
congenital diaphragmatic hernia
wt1
diaphragm development
prx1-cre
mesenchyme
mouse model
Online Access:http://dmm.biologists.org/content/14/1/dmm046797

Internet

http://dmm.biologists.org/content/14/1/dmm046797

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