Bone marrow-derived mesenchymal stem cell and simvastatin treatment leads to improved functional recovery and modified c-Fos expression levels in the brain following ischemic stroke

Bone marrow-derived mesenchymal stem cell and simvastatin treatment leads to improved functional recovery and modified c-Fos expression levels in the brain following ischemic stroke

Objective(s): The beneficial outcomes of bone marrow-derived mesenchymal stem cell (BMSC) treatment on functional recovery following stroke has been well established. Furthermore, 5-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors have also been shown to increase neuronal survival...

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Bibliographic Details
Main Authors: Gila Pirzad Jahromi, Alireza Shabanzadeh Pirsaraei, Mina Mokhtari Hashtjini, Seyed Shahabeddin Sadr, Javad Rasouli Vani, Javad Raouf Sarshoori, Jason Charish
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-10-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Behavioral assessment
Bone marrow stromal cell
Brain
c-Fos
Ischemic stroke
Simvastatin
Online Access:http://ijbms.mums.ac.ir/article_11355_2007d6da3c179ed0109231bf38352928.pdf

Internet

http://ijbms.mums.ac.ir/article_11355_2007d6da3c179ed0109231bf38352928.pdf

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