Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages.

The battle against malaria has been substantially impeded by the recurrence of drug resistance in Plasmodium falciparum, the deadliest human malaria parasite. To counter the problem, novel antimalarial drugs are urgently needed, especially those that target unique pathways of the parasite, since the...

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Bibliographic Details
Main Authors: Hangjun Ke, Suresh M Ganesan, Swati Dass, Joanne M Morrisey, Sovitj Pou, Aaron Nilsen, Michael K Riscoe, Michael W Mather, Akhil B Vaidya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214023