The effect of comorbidities for the prognosis of community-acquired pneumonia: an epidemiologic study using a hospital surveillance in Japan
Abstract Objective Pneumonia is a common but serious illness that continues to present significant morbidity and mortality. Although the effect of severity at admission on outcome has been well reported, the role of comorbidity is still not widely understood. The Charlson Comorbidity Index measures...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
|
Series: | BMC Research Notes |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13104-019-4848-1 |
id |
doaj-9634475fcc34402a9acdbec329f1ed43 |
---|---|
record_format |
Article |
spelling |
doaj-9634475fcc34402a9acdbec329f1ed432020-12-20T12:34:18ZengBMCBMC Research Notes1756-05002019-12-011211510.1186/s13104-019-4848-1The effect of comorbidities for the prognosis of community-acquired pneumonia: an epidemiologic study using a hospital surveillance in JapanMai Thi Ngoc Nguyen0Nobuyuki Saito1Yukiko Wagatsuma2Department of Clinical Trials and Clinical Epidemiology, Graduate School of Comprehensive Human Sciences, University of TsukubaThe Shock and Trauma Center, Nippon Medical School Chiba Hokusoh HospitalDepartment of Clinical Trials and Clinical Epidemiology, Faculty of Medicine, University of TsukubaAbstract Objective Pneumonia is a common but serious illness that continues to present significant morbidity and mortality. Although the effect of severity at admission on outcome has been well reported, the role of comorbidity is still not widely understood. The Charlson Comorbidity Index measures comorbidity with a well-established history of predicting long-term outcome but its utility in pneumonia prognosis is still limited. Here, we use the Charlson Comorbidity Index and hospital surveillance data to investigate associations between comorbidities and in-hospital mortality due to community-acquired pneumonia. Results Among the 535 eligible adult patients (69.0% male, median [IQR] age, 79 [70–84] years), 100 (18.7%) acquired severe to extremely severe pneumonia. The median [IQR] CCI was 1 [1–3]. Malignancy (129 of 535, 24.1%), chronic pulmonary diseases (113 of 535, 21.1%) and congestive heart failure (103 of 535, 19.3%) were frequent. Higher Charlson Comorbidity Index scores were associated with higher risk of in-hospital mortality (OR 1.28; 95% CI 1.07–1.53). These results support the inclusion of comorbid burden in predicting community-acquired pneumonia outcome.https://doi.org/10.1186/s13104-019-4848-1Community-acquired pneumoniaMortalityComorbidityCharlson Comorbidity Index |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mai Thi Ngoc Nguyen Nobuyuki Saito Yukiko Wagatsuma |
spellingShingle |
Mai Thi Ngoc Nguyen Nobuyuki Saito Yukiko Wagatsuma The effect of comorbidities for the prognosis of community-acquired pneumonia: an epidemiologic study using a hospital surveillance in Japan BMC Research Notes Community-acquired pneumonia Mortality Comorbidity Charlson Comorbidity Index |
author_facet |
Mai Thi Ngoc Nguyen Nobuyuki Saito Yukiko Wagatsuma |
author_sort |
Mai Thi Ngoc Nguyen |
title |
The effect of comorbidities for the prognosis of community-acquired pneumonia: an epidemiologic study using a hospital surveillance in Japan |
title_short |
The effect of comorbidities for the prognosis of community-acquired pneumonia: an epidemiologic study using a hospital surveillance in Japan |
title_full |
The effect of comorbidities for the prognosis of community-acquired pneumonia: an epidemiologic study using a hospital surveillance in Japan |
title_fullStr |
The effect of comorbidities for the prognosis of community-acquired pneumonia: an epidemiologic study using a hospital surveillance in Japan |
title_full_unstemmed |
The effect of comorbidities for the prognosis of community-acquired pneumonia: an epidemiologic study using a hospital surveillance in Japan |
title_sort |
effect of comorbidities for the prognosis of community-acquired pneumonia: an epidemiologic study using a hospital surveillance in japan |
publisher |
BMC |
series |
BMC Research Notes |
issn |
1756-0500 |
publishDate |
2019-12-01 |
description |
Abstract Objective Pneumonia is a common but serious illness that continues to present significant morbidity and mortality. Although the effect of severity at admission on outcome has been well reported, the role of comorbidity is still not widely understood. The Charlson Comorbidity Index measures comorbidity with a well-established history of predicting long-term outcome but its utility in pneumonia prognosis is still limited. Here, we use the Charlson Comorbidity Index and hospital surveillance data to investigate associations between comorbidities and in-hospital mortality due to community-acquired pneumonia. Results Among the 535 eligible adult patients (69.0% male, median [IQR] age, 79 [70–84] years), 100 (18.7%) acquired severe to extremely severe pneumonia. The median [IQR] CCI was 1 [1–3]. Malignancy (129 of 535, 24.1%), chronic pulmonary diseases (113 of 535, 21.1%) and congestive heart failure (103 of 535, 19.3%) were frequent. Higher Charlson Comorbidity Index scores were associated with higher risk of in-hospital mortality (OR 1.28; 95% CI 1.07–1.53). These results support the inclusion of comorbid burden in predicting community-acquired pneumonia outcome. |
topic |
Community-acquired pneumonia Mortality Comorbidity Charlson Comorbidity Index |
url |
https://doi.org/10.1186/s13104-019-4848-1 |
work_keys_str_mv |
AT maithingocnguyen theeffectofcomorbiditiesfortheprognosisofcommunityacquiredpneumoniaanepidemiologicstudyusingahospitalsurveillanceinjapan AT nobuyukisaito theeffectofcomorbiditiesfortheprognosisofcommunityacquiredpneumoniaanepidemiologicstudyusingahospitalsurveillanceinjapan AT yukikowagatsuma theeffectofcomorbiditiesfortheprognosisofcommunityacquiredpneumoniaanepidemiologicstudyusingahospitalsurveillanceinjapan AT maithingocnguyen effectofcomorbiditiesfortheprognosisofcommunityacquiredpneumoniaanepidemiologicstudyusingahospitalsurveillanceinjapan AT nobuyukisaito effectofcomorbiditiesfortheprognosisofcommunityacquiredpneumoniaanepidemiologicstudyusingahospitalsurveillanceinjapan AT yukikowagatsuma effectofcomorbiditiesfortheprognosisofcommunityacquiredpneumoniaanepidemiologicstudyusingahospitalsurveillanceinjapan |
_version_ |
1724376397848248320 |