An Integrative Approach to Treat Parkinson's Disease: Ukgansan Complements L-Dopa by Ameliorating Dopaminergic Neuronal Damage and L-Dopa-Induced Dyskinesia in Mice

An Integrative Approach to Treat Parkinson's Disease: Ukgansan Complements L-Dopa by Ameliorating Dopaminergic Neuronal Damage and L-Dopa-Induced Dyskinesia in Mice

Parkinson's disease (PD) is accompanied by motor impairments due to the loss of dopaminergic neurons in the nigrostriatal pathway. Levodopa (L-dopa) has been the gold standard therapy for PD since the 1960s; however, its neurotoxic features accelerate PD progression through auto-oxidation or th...

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Bibliographic Details
Main Authors: Eugene Huh, Jin Gyu Choi, Yeomoon Sim, Myung Sook Oh
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson's disease
levodopa
ukgansan
levodopa-induced dyskinesia
6-hydroxydopamine
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00431/full

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https://www.frontiersin.org/article/10.3389/fnagi.2018.00431/full

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