Huaier Extract Induces Autophagic Cell Death by Inhibiting the mTOR/S6K Pathway in Breast Cancer Cells.

Huaier extract is attracting increased attention due to its biological activities, including antitumor, anti-parasite and immunomodulatory effects. Here, we investigated the role of autophagy in Huaier-induced cytotoxicity in MDA-MB-231, MDA-MB-468 and MCF7 breast cancer cells. Huaier treatment inhi...

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Bibliographic Details
Main Authors: Xiaolong Wang, Wenwen Qi, Yaming Li, Ning Zhang, Lun Dong, Mingjuan Sun, Jinjing Cun, Yan Zhang, Shangge Lv, Qifeng Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4489895?pdf=render