Evaluation of brain-derived neurotrophic factor expression and spatial memory after valproic acid administration in animal model of hippocampal degeneration

Background: Hippocampal neurodegeneration caused the incidence of cognitive deficits, along with a possible decrease of neurotrophins. Valproic acid (VPA) is a histone deacetylase inhibitor, which could protect the nervous system from neuronal degeneration through neurotrophic modifications. This st...

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Bibliographic Details
Main Authors: Mohammad Amin Edalatmanesh, Mahtab Sheikholeslami, Samaneh Rafiei
Format: Article
Language:fas
Published: Kashan University of Medical Sciences and Health Services 2018-08-01
Series:Fiyz̤
Subjects:
Rat
Online Access:http://feyz.kaums.ac.ir/article-1-3487-en.html