Different Storing and Processing Conditions of Human Lymphocytes do not Alter P-Glycoprotein Rhodamine 123 Efflux.

Different Storing and Processing Conditions of Human Lymphocytes do not Alter P-Glycoprotein Rhodamine 123 Efflux.

P-glycoprotein (Pgp), a protein codified by Multi Drug Resistance (MDR1) gene, has a detoxifying function and might influence the toxicity and pharmacokinetics and pharmacodynamics of drugs. Sampling strategies to improve Pgp studies could be useful to optimize the sensitivity and the reproducibilit...

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Bibliographic Details
Main Authors: Gemma Chiva-Blanch, Pepita Giménez-Bonafe, Inés Llaudó, Joan Torras, Josep M Cruzado, Jordi Pétriz, Esther Castaño, Marcella Franquesa, Avelina Tortosa, Immaculada Herrero-Fresneda, Inés Rama, Oriol Bestard, Josep M Grinyó, Núria LLoberas
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2009-11-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/6263

Internet

https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/6263

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