Colorimetric RT-LAMP SARS-CoV-2 diagnostic sensitivity relies on color interpretation and viral load

Colorimetric RT-LAMP SARS-CoV-2 diagnostic sensitivity relies on color interpretation and viral load

Abstract The use of RT-LAMP (reverse transcriptase—loop mediated isothermal amplification) has been considered as a promising point-of-care method to diagnose COVID-19. In this manuscript we show that the RT-LAMP reaction has a sensitivity of only 200 RNA virus copies, with a color change from pink...

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Bibliographic Details
Main Authors: Mateus Nóbrega Aoki, Bruna de Oliveira Coelho, Luiz Gustavo Bentim Góes, Paola Minoprio, Edison Luiz Durigon, Luis Gustavo Morello, Fabricio Klerynton Marchini, Irina Natassja Riediger, Maria do Carmo Debur, Helder I. Nakaya, Lucas Blanes
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88506-y

Internet

https://doi.org/10.1038/s41598-021-88506-y

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