Synthesis and computer - aided drug design studies of novel thiosemicarbazide derivatives as potent and target - oriented anti - cancer agents

A series of novel thiosemicarbazide derivatives (2a-d) were synthesized from 3,5-bis(trifluoromethyl) benzohydrazide (1) and various substituted isothiocyanates. The structures of novel compounds were determined by analytical and spectral (IR, 1H-NMR, and elemental analysis) methods. In silico studi...

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Bibliographic Details
Main Authors: Efe Dogukan Dincel, Nuray Ulusoy Guzeldemirci
Format: Article
Language:English
Published: Society of TURAZ AKADEMI 2020-06-01
Series:Medicine Science
Subjects:
Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=65189