Cytoprotective Preconditioning of Osteoblast-Like Cells with <i>N</i>-Acetyl-<i>L</i>-Cysteine for Bone Regeneration in Cell Therapy

Cytoprotective Preconditioning of Osteoblast-Like Cells with <i>N</i>-Acetyl-<i>L</i>-Cysteine for Bone Regeneration in Cell Therapy

Oxidative stress hinders tissue regeneration in cell therapy by inducing apoptosis and dysfunction in transplanted cells. <i>N</i>-acetyl-<i>L</i>-cysteine (NAC) reinforces cellular antioxidant capabilities by increasing a major cellular endogenous antioxidant molecule, gluta...

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Bibliographic Details
Main Authors: Masahiro Yamada, Jun Watanabe, Takeshi Ueno, Takahiro Ogawa, Hiroshi Egusa
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
acute inflammation
apoptosis
cell fate
glutathione
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/20/20/5199

Internet

https://www.mdpi.com/1422-0067/20/20/5199

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