Mycobacteria exploit host hyaluronan for efficient extracellular replication.

In spite of the importance of hyaluronan in host protection against infectious organisms in the alveolar spaces, its role in mycobacterial infection is unknown. In a previous study, we found that mycobacteria interact with hyaluronan on lung epithelial cells. Here, we have analyzed the role of hyalu...

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Main Authors: Yukio Hirayama, Mamiko Yoshimura, Yuriko Ozeki, Isamu Sugawara, Tadashi Udagawa, Satoru Mizuno, Naoki Itano, Koji Kimata, Aki Tamaru, Hisashi Ogura, Kazuo Kobayashi, Sohkichi Matsumoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2763203?pdf=render