DNA methylation affects metastasis of renal cancer and is associated with TGF-β/RUNX3 inhibition

DNA methylation affects metastasis of renal cancer and is associated with TGF-β/RUNX3 inhibition

Abstract Background Renal cell carcinoma accounts for 2–3% of all cancers and metastasis increased the malignancy of renal cancer. However, the role of methylation in metastasis of renal cancer is poorly understood. Methods We performed targeted gene array to compare the differential expressions of...

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Bibliographic Details
Main Authors: Jianbo Zheng, Yanhui Mei, Ping Xiang, Guangsheng Zhai, Ning Zhao, Chuanbing Xu, Min Liu, Zhengsheng Pan, Kai Tang, Dongsheng Jia
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Cancer Cell International
Subjects:
Renal cancer
Methylation
RUNX3
TGF-β
Metastasis
CpG
Online Access:http://link.springer.com/article/10.1186/s12935-018-0554-7

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http://link.springer.com/article/10.1186/s12935-018-0554-7

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