Downregulation by CNNM2 of ATP5MD expression in the 10q24.32 schizophrenia-associated locus involved in impaired ATP production and neurodevelopment

Abstract Genome-wide association studies (GWAS) have accelerated the discovery of numerous genetic variants associated with schizophrenia. However, most risk variants show a small effect size (odds ratio (OR) <1.2), suggesting that more functional risk variants remain to be identified. Here, we e...

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Bibliographic Details
Main Authors: Zhongju Wang, Yongchang Zhu, Linyan Ye, Qiyang Li, Bo Guo, Hao Zhao, Xiuqin Bao, Qiqi Zhuo, Tengfei Yang, Zhaoqiang Li, Shufen Li, Bingtao Hao, Cunyou Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:npj Schizophrenia
Online Access:https://doi.org/10.1038/s41537-021-00159-y