Comparative Immunogenicity of the Tetanus Toxoid and Recombinant Tetanus Vaccines in Mice, Rats, and Cynomolgus Monkeys

Tetanus is caused by the tetanus neurotoxin (TeNT) and is one of the most dreaded diseases especially in the developing countries. The current vaccine against tetanus is based on an inactivated tetanus toxin, which is effective but has many drawbacks. In our previous study, we developed a recombinan...

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Bibliographic Details
Main Authors: Rui Yu, Ting Fang, Shuling Liu, Xiaohong Song, Changming Yu, Jianmin Li, Ling Fu, Lihua Hou, Junjie Xu, Wei Chen
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/8/7/194