Novel association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns

Novel association of TM6SF2 rs58542926 genotype with increased serum tyrosine levels and decreased apoB-100 particles in Finns

A glutamate-to-lysine variant (rs58542926-T) in transmembrane 6 superfamily member 2 (TM6SF2) is associated with increased fatty liver disease and diabetes in conjunction with decreased cardiovascular disease risk. To identify mediators of the effects of TM6SF2, we tested for associations between rs...

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Bibliographic Details
Main Authors: Daniel Seung Kim, Anne U. Jackson, Yatong K. Li, Heather M. Stringham, Johanna Kuusisto, Antti J. Kangas, Pasi Soininen, Mika Ala-Korpela, Charles F. Burant, Veikko Salomaa, Michael Boehnke, Markku Laakso, Elizabeth K. Speliotes
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Journal of Lipid Research
Subjects:
transmembrane 6 superfamily member 2
nonalcoholic fatty liver disease
epidemiology
cardiovascular disease
type 2 diabetes
apolipoprotein B-100
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520335963

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http://www.sciencedirect.com/science/article/pii/S0022227520335963

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