Cerebrospinal Fluid-Derived Microvesicles From Sleeping Sickness Patients Alter Protein Expression in Human Astrocytes

Cerebrospinal Fluid-Derived Microvesicles From Sleeping Sickness Patients Alter Protein Expression in Human Astrocytes

Human African trypanosomiasis (HAT) caused by the extracellular protozoon Trypanosoma brucei, is a neglected tropical disease affecting the poorest communities in sub-Saharan Africa. HAT progresses from a hemolymphatic first stage (S1) to a meningo-encephalitic late stage (S2) when parasites reach t...

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Bibliographic Details
Main Authors: Vito Dozio, Veerle Lejon, Dieudonné Mumba Ngoyi, Philippe Büscher, Jean-Charles Sanchez, Natalia Tiberti
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
human African trypanosomiasis
microvesicles
cerebrospinal fluid
DIA-MS
astrocytes
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00391/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00391/full

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