Pancreatic Stellate Cells: A Rising Translational Physiology Star as a Potential Stem Cell Type for Beta Cell Neogenesis

Pancreatic Stellate Cells: A Rising Translational Physiology Star as a Potential Stem Cell Type for Beta Cell Neogenesis

The progressive decline and eventual loss of islet β-cell function underlies the pathophysiological mechanism of the development of both type 1 and type 2 diabetes mellitus. The recovery of functional β-cells is an important strategy for the prevention and treatment of diabetes. Based on similaritie...

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Bibliographic Details
Main Authors: Yunting Zhou, Bo Sun, Wei Li, Junming Zhou, Feng Gao, Xiaohang Wang, Min Cai, Zilin Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Physiology
Subjects:
pancreatic stellate cell
quiescent
activation
stem/progenitor cell
physiological functions
β-cells neogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00218/full

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https://www.frontiersin.org/article/10.3389/fphys.2019.00218/full

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