H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis

H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis

Cell-type-specific 3D organization of the genome is unrecognizable during mitosis. It remains unclear how essential positional information is transmitted through cell division such that a daughter cell recapitulates the spatial genome organization of the parent. Lamina-associated domains (LADs) are...

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Bibliographic Details
Main Authors: Andrey Poleshko, Cheryl L Smith, Son C Nguyen, Priya Sivaramakrishnan, Karen G Wong, John Isaac Murray, Melike Lakadamyali, Eric F Joyce, Rajan Jain, Jonathan A Epstein
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-10-01
Series:eLife
Subjects:
nuclear architecture
H3K9me2
mitosis
genome organization
peripheral heterochromatin
nuclear lamina
Online Access:https://elifesciences.org/articles/49278

Internet

https://elifesciences.org/articles/49278

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