Joint latent class model: Simulation study of model properties and application to amyotrophic lateral sclerosis disease

Joint latent class model: Simulation study of model properties and application to amyotrophic lateral sclerosis disease

Abstract Background In many clinical applications, evolution of a longitudinal marker is censored by an event occurrence, and, symmetrically, event occurrence can be influenced by the longitudinal marker evolution. In such frameworks joint modeling is of high interest. The Joint Latent Class Model (...

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Bibliographic Details
Main Authors: Maéva Kyheng, Génia Babykina, Camille Ternynck, David Devos, Julien Labreuche, Alain Duhamel
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Medical Research Methodology
Subjects:
Joint model
Latent classes
Survival analysis
Linear mixed model
MLE properties
Monte Carlo simulations
Online Access:https://doi.org/10.1186/s12874-021-01377-9

Internet

https://doi.org/10.1186/s12874-021-01377-9

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