Xenogeneic graft-versus-host-disease in NOD-scid IL-2Rγnull mice display a T-effector memory phenotype.

The occurrence of Graft-versus-Host Disease (GvHD) is a prevalent and potentially lethal complication that develops following hematopoietic stem cell transplantation. Humanized mouse models of xenogeneic-GvHD based upon immunodeficient strains injected with human peripheral blood mononuclear cells (...

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Bibliographic Details
Main Authors: Niwa Ali, Barry Flutter, Robert Sanchez Rodriguez, Ehsan Sharif-Paghaleh, Linda D Barber, Giovanna Lombardi, Frank O Nestle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3429415?pdf=render