Characterization of JAK1 Pseudokinase Domain in Cytokine Signaling
The Janus kinase-signal transducer and activator of transcription protein (JAK-STAT) pathway mediates essential biological functions from immune responses to haematopoiesis. Deregulated JAK-STAT signaling causes myeloproliferative neoplasms, leukaemia, and lymphomas, as well as autoimmune diseases....
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-12-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/1/78 |