Mouse aging cell atlas analysis reveals global and cell type-specific aging signatures

Aging is associated with complex molecular and cellular processes that are poorly understood. Here we leveraged the Tabula Muris Senis single-cell RNA-seq data set to systematically characterize gene expression changes during aging across diverse cell types in the mouse. We identified aging-dependen...

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Bibliographic Details
Main Authors: Martin Jinye Zhang, Angela Oliveira Pisco, Spyros Darmanis, James Zou
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/62293