Modeling of osteosarcoma with induced pluripotent stem cells

Osteosarcoma is the most common type of bone cancer. Osteosarcoma is commonly associated with TP53 inactivation (around 95% of cases) and RB1 inactivation (around 28% of cases). With the discovery of reprogramming factors to induce pluripotency even in terminally differentiated cells, induced plurip...

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Bibliographic Details
Main Authors: Lon Kai Pang, Mezthly Pena, Ruiying Zhao, Dung-Fang Lee
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Stem Cell Research
Subjects:
H19
Online Access:http://www.sciencedirect.com/science/article/pii/S187350612030307X