Psoromic Acid, a Lichen-Derived Molecule, Inhibits the Replication of HSV-1 and HSV-2, and Inactivates HSV-1 DNA Polymerase: Shedding Light on Antiherpetic Properties

Psoromic Acid, a Lichen-Derived Molecule, Inhibits the Replication of HSV-1 and HSV-2, and Inactivates HSV-1 DNA Polymerase: Shedding Light on Antiherpetic Properties

Psoromic acid (PA), a bioactive lichen-derived compound, was investigated for its inhibitory properties against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), along with the inhibitory effect on HSV-1 DNA polymerase, which is a key enzyme that plays an essential role in HSV-1 replication cy...

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Bibliographic Details
Main Authors: Sherif T. S. Hassan, Miroslava Šudomová, Kateřina Berchová-Bímová, Karel Šmejkal, Javier Echeverría
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Molecules
Subjects:
antiherpetic
anti-enzymatic properties
lichen metabolites
HSV
HSV replication
psoromic acid
Online Access:https://www.mdpi.com/1420-3049/24/16/2912

Internet

https://www.mdpi.com/1420-3049/24/16/2912

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