Cytochrome P450 1A2 Metabolizes 17β-Estradiol to Suppress Hepatocellular Carcinoma.

Cytochrome P450 1A2 Metabolizes 17β-Estradiol to Suppress Hepatocellular Carcinoma.

Hepatocellular carcinoma (HCC) occurs more frequently in men than in women. It is commonly agreed that estrogen plays important roles in suppressing HCC development, however, the underlying mechanism remains largely unknown. Since estrogen is mainly metabolized in liver and its metabolites affect ce...

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Bibliographic Details
Main Authors: Jianwai Ren, George G Chen, Yi Liu, Xianwei Su, Baoguang Hu, Billy C S Leung, Y Wang, Rocky L K Ho, Shengli Yang, Gang Lu, C G Lee, Paul B S Lai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4836701?pdf=render

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http://europepmc.org/articles/PMC4836701?pdf=render

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