Linking single-cell measurements of mass, growth rate, and gene expression

Linking single-cell measurements of mass, growth rate, and gene expression

Abstract Mass and growth rate are highly integrative measures of cell physiology not discernable via genomic measurements. Here, we introduce a microfluidic platform enabling direct measurement of single-cell mass and growth rate upstream of highly multiplexed single-cell profiling such as single-ce...

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Bibliographic Details
Main Authors: Robert J. Kimmerling, Sanjay M. Prakadan, Alejandro J. Gupta, Nicholas L. Calistri, Mark M. Stevens, Selim Olcum, Nathan Cermak, Riley S. Drake, Kristine Pelton, Frederik De Smet, Keith L. Ligon, Alex K. Shalek, Scott R. Manalis
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Genome Biology
Subjects:
Single-cell RNA-Seq
Mass
Growth
Serial suspended microchannel resonator
Multi-omics
Single cell
Online Access:http://link.springer.com/article/10.1186/s13059-018-1576-0

Internet

http://link.springer.com/article/10.1186/s13059-018-1576-0

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