Longitudinal [18F]FDG-PET/CT analysis of the glucose metabolism in ApoE-deficient mice

Longitudinal [18F]FDG-PET/CT analysis of the glucose metabolism in ApoE-deficient mice

Abstract Background Strong line of evidence suggests that the increased risk to develop AD may at least be partly mediated by cholesterol metabolism. A key regulator of cholesterol transport is the Apolipoprotein E4 (ApoE4), which plays a fundamental role in neuronal maintenance and repair. Impaired...

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Bibliographic Details
Main Authors: Angela Kuhla, Lou Meuth, Jan Stenzel, Tobias Lindner, Chris Lappe, Jens Kurth, Bernd J. Krause, Stefan Teipel, Änne Glass, Guenther Kundt, Brigitte Vollmar
Format: Article
Language:English
Published: SpringerOpen 2020-10-01
Series:EJNMMI Research
Subjects:
Cerebral glucose metabolism
[18F]FDG-PET/CT imaging
Proton magnetic resonance spectroscopy
Brain stem
ApoE-deficiency
Online Access:http://link.springer.com/article/10.1186/s13550-020-00711-4

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http://link.springer.com/article/10.1186/s13550-020-00711-4

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