The Use of Heptamethine Cyanine Dyes as Drug-Conjugate Systems in the Treatment of Primary and Metastatic Brain Tumors

The Use of Heptamethine Cyanine Dyes as Drug-Conjugate Systems in the Treatment of Primary and Metastatic Brain Tumors

Effective cancer therapeutics for brain tumors must be able to cross the blood-brain barrier (BBB) to reach the tumor in adequate quantities and overcome the resistance conferred by the local tumor microenvironment. Clinically approved chemotherapeutic agents have been investigated for brain neoplas...

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Bibliographic Details
Main Authors: Elizabeth Cooper, Peter J. Choi, William A. Denny, Jiney Jose, Mike Dragunow, Thomas I.-H. Park
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
heptamethine cyanine dyes
conjugation
drug delivery
brain metastases
primary brain tumor
chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.654921/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.654921/full

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