Stage-Specific Role of <i>Amelx</i> Activation in Stepwise Ameloblast Induction from Mouse Induced Pluripotent Stem Cells

Stage-Specific Role of <i>Amelx</i> Activation in Stepwise Ameloblast Induction from Mouse Induced Pluripotent Stem Cells

Amelogenin comprises ~90% of enamel proteins; however, the involvement of <i>Amelx</i> transcriptional activation in regulating ameloblast differentiation from induced pluripotent stem cells (iPSCs) remains unknown. In this study, we generated doxycycline-inducible <i>Amelx</i&g...

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Bibliographic Details
Main Authors: Xinchao Miao, Kunimichi Niibe, Maolin Zhang, Zeni Liu, Praphawi Nattasit, Yumi Ohori-Morita, Takashi Nakamura, Xinquan Jiang, Hiroshi Egusa
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
ameloblast
amelogenin
cell adhesion
cell differentiation
induced pluripotent stem cells
transcriptional activation
Online Access:https://www.mdpi.com/1422-0067/22/13/7195

Internet

https://www.mdpi.com/1422-0067/22/13/7195

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