Prostate Cancer and Li-Fraumeni Syndrome: Implications for Screening and Therapy

Li-Fraumeni Syndrome (LFS) is an autosomal dominant genetic disorder associated with mutations in the TP53 gene and characterized by a propensity to develop a variety of malignancies resulting in a shortened lifespan. We report a case of prostate cancer in a 50 year old male with LFS. Experimental s...

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Bibliographic Details
Main Authors: Colleen K. Spees, Kelly J. Kelleher, Ronney Abaza, Steven K. Clinton
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Urology Case Reports
Subjects:
p53
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442015000030