Role of haptoglobin in polycystic ovary syndrome (PCOS), obesity and disorders of glucose tolerance in premenopausal women.

<h4>Background</h4>Hp(2) alleles of the haptoglobin alpha-chain polymorphism reduce the anti-oxidant properties and increase the pro-inflammatory actions of this acute-phase protein in a gene-dosage fashion. We hypothesized that the haptoglobin polymorphism might contribute to the increa...

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Bibliographic Details
Main Authors: Francisco Alvarez-Blasco, Ma Angeles Martínez-García, Manuel Luque-Ramírez, Naiara Parraza, José L San Millán, Héctor F Escobar-Morreale
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19440331/pdf/?tool=EBI