New Oral Formulation and in Vitro Evaluation of Docetaxel-Loaded Nanomicelles

Intravenous administration of Taxotere® (a commercial form of docetaxel, DTX) leads to many problems such as hypersensitivity, hemolysis, cutaneous allergy, and patient refusal due to its prolonged injection. The oral absorption of DTX is very low due to its hydrophobic nature. The purpose of this s...

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Bibliographic Details
Main Authors: Atefeh Hekmat, Hossein Attar, Ali Akbar Seyf Kordi, Maryam Iman, Mahmoud Reza Jaafari
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/9/1265