Discovery of Pancreatic Ductal Adenocarcinoma-Related Aberrant Glycosylations: A Multilateral Approach of Lectin Microarray-Based Tissue Glycomic Profiling With Public Transcriptomic Datasets

Discovery of Pancreatic Ductal Adenocarcinoma-Related Aberrant Glycosylations: A Multilateral Approach of Lectin Microarray-Based Tissue Glycomic Profiling With Public Transcriptomic Datasets

Aberrant protein glycosylation is one of the most notable features in cancerous tissues, and thereby glycoproteins with disease-relevant glycosylation alterations are fascinating targets for the development of biomarkers and therapeutic agents. For this purpose, a reliable strategy is needed for the...

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Bibliographic Details
Main Authors: Takanori Wagatsuma, Chiaki Nagai-Okatani, Atsushi Matsuda, Yohei Masugi, Masako Imaoka, Ken Yamazaki, Michiie Sakamoto, Atsushi Kuno
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Oncology
Subjects:
multi-omics
glycosylation
lectin microarray
ABO blood group antigen
The Cancer Genome Atlas (TCGA)
Genotype-Tissue Expression (GTEx)
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00338/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.00338/full

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