Adult restoration of Shank3 expression rescues selective autistic-like phenotypes

Adult restoration of Shank3 expression rescues selective autistic-like phenotypes

Because autism spectrum disorders are neurodevelopmental disorders and patients typically display symptoms before the age of three, one of the key questions in autism research is whether the pathology is reversible in adults. Here we investigate the developmental requirement of Shank3 in mice, a pro...

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Bibliographic Details
Main Authors: Mei, Yuan (Contributor), Monteiro, Patricia (Contributor), Zhou, Yang (Contributor), Kim, Jinah (Contributor), Gao, Xian (Contributor), Fu, Zhanyan (Contributor), Feng, Guoping (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), McGovern Institute for Brain Research at MIT (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-11-21T20:37:02Z.
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