Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

<jats:title>Abstract</jats:title><jats:p>Leptomeningeal disease (LMD) is a devastating complication of solid tumor malignancies, with dire prognosis and no effective systemic treatment options. Over the past decade, the incidence of LMD has steadily increased due to therapeutics th...

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Main Authors: Prakadan, Sanjay M (Author), Alvarez-Breckenridge, Christopher A (Author), Markson, Samuel C (Author), Kim, Albert E (Author), Klein, Robert H (Author), Nayyar, Naema (Author), Navia, Andrew W (Author), Kuter, Benjamin M (Author), Kolb, Kellie E (Author), Bihun, Ivanna (Author), Mora, Joana L (Author), Bertalan, Mia Solana (Author), Shaw, Brian (Author), White, Michael (Author), Kaplan, Alexander (Author), Stocking, Jackson H (Author), Wadsworth, Marc H (Author), Lee, Eudocia Q (Author), Chukwueke, Ugonma (Author), Wang, Nancy (Author), Subramanian, Megha (Author), Rotem, Denisse (Author), Cahill, Daniel P (Author), Adalsteinsson, Viktor A (Author), Miller, Jeffrey W (Author), Sullivan, Ryan J (Author), Carter, Scott L (Author), Brastianos, Priscilla K (Author), Shalek, Alex K (Author)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2022-03-18T14:13:50Z.
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