Sulforaphane-Mediated Reduction of Aflatoxin B-1-N-7-Guanine in Rat Liver DNA: Impacts of Strain and Sex

Sulforaphane-Mediated Reduction of Aflatoxin B-1-N-7-Guanine in Rat Liver DNA: Impacts of Strain and Sex

Aflatoxin B1 (AFB1) is a DNA-binding toxin that contributes to the burden of liver cancer in tropical areas. AFB1-DNA adducts are powerful biomarkers that discern individual and population risk from exposure to this carcinogen. The discovery of concordance between the metabolic pathways of the male...

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Main Authors: Fiala, Jeannette Louise Allen (Contributor), Egner, Patricia A. (Author), Wiriyachan, Nirachara (Author), Ruchirawat, Mathuros (Author), Kensler, Kevin H. (Author), Wogan, Gerald N. (Contributor), Groopman, John D. (Author), Croy, Robert G. (Contributor), Essigmann, John M. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Oxford University Press, 2012-10-15T20:09:29Z.
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