A Continuous Homologation of Esters: An Efficient Telescoped Reduction-Olefination Sequence
A continuous protocol for the two-carbon homologation of esters to α,β-unsaturated esters is described. This multireactor homologation telescopes an ester reduction, phosphonate deprotonation, and Horner-Wadsworth-Emmons olefination, thus converting a three-operation procedure into a single, uninter...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society (ACS),
2013-01-17T18:18:32Z.
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| Subjects: | |
| Online Access: | Get fulltext |