Structure Activity Relationship Studies on Isoform Selective Sphingosine Kinase Inhibitors
A variety of diseases including Alzheimer's disease, asthma, cancer, fibrosis, multiple sclerosis, and sickle cell disease have been associated with elevated levels of sphingosine-1-phosphate (S1P). S1P, a pleiotropic lipid mediator involved in a broad range of cellular processes, is synthesize...
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| Format: | Others |
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Virginia Tech
2018
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| Online Access: | http://hdl.handle.net/10919/82129 |