GENOTOXICITY OF THE PYRROLIZIDINE ALKALOIDS: ASSOCIATION WITH ADVERSE HEPATIC EFFECTS (ALKALINE ELUTION, CHEMICAL CARCINOGENESIS, ANTIMITOTIC EFFECTS).
Pyrrolizidine alkaloids (PAs) produce a variety adverse hepatic effects, including acute toxicity, carcinogenicity and potent, persistent antimitotic effects. Additionally several have been evaluated as antineoplastic agents. PAs constitute significant health hazards to man and domestic animals. The...
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| Language: | en |
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The University of Arizona.
1984
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| Online Access: | http://hdl.handle.net/10150/187838 |