Methods for Rapid Protein Depletion in C. elegans using Auxin-Inducible Degradation

Numerous methods have been developed in model systems to deplete or inactivate proteins to elucidate their functional roles. In Caenorhabditis elegans, a common method for protein depletion is RNA interference (RNAi), in which mRNA is targeted for degradation. C. elegans is also a powerful genetic o...

Full description

Bibliographic Details
Main Authors: Divekar, N.S (Author), Horton, H.E (Author), Wignall, S.M (Author)
Format: Article
Language:English
Published: Blackwell Publishing Inc. 2021
Subjects:
AID
Online Access:View Fulltext in Publisher